Cannabis & Cognitive Functioning by Nadia Solowij

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By Nadia Solowij

Hashish is the main usual illicit substance on the planet, however the query of no matter if its long-term use may end up in lasting and irreparable cognitive impairment continues to be arguable. This well timed and well-argued quantity offers an intensive and entire serious overview of the literature proper to hashish and cognitive functioning, interpreting the proof within the mild of significant contemporary findings within the pharmacology and neuropsychology of hashish. unique experiences performed by means of the writer are provided, using essentially the most glossy and delicate options on hand to evaluate cognitive functioning--the use of event-related potentials or ERPs. The author's end, that long-term hashish use might produce irreversible impairment in reminiscence, realization and the association and integration of advanced capabilities, may be of compelling curiosity to quite a lot of clinicians, researchers and coverage makers.

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A further difficulty with animal studies is a consequence of differences between animals and humans in route of cannabinoid administration.

1986). For example, blood levels of THC may decline to 2 ng/ml 1 hour after smoking a low potency cannabis cigarette, a level that may be achieved only 9 hours after smoking a high potency cannabis Detection of cannabinoids in body fluids 25 cigarette (Hawks, 1982; Perez-Reyes et ai, 1982). In habitual and chronic users such levels may persist for several days after use because of the slow release of accumulated THC. The detection of THC in blood above 10-15 ng/ml provides presumptive evidence of "recent" consumption of cannabis but it is not possible to determine how recently it was consumed.

It is probably safe to assume that the most common route of administration in the culturally similar English speaking countries reviewed above is by smoking, and the most widely used form of the drug is marijuana. Anecdotal evidence suggests that hashish is far more prevalent in the UK, while Australia favours heads and New Zealand manufactures substantial quantities of hash oil. e. most users use the drug to experience its euphoric and relaxing effects on a limited number of occasions only. Most of those who have tried cannabis either discontinue their use after a small number of occasions or, if they continue to use, do so intermittently and episodically whenever the drug is available.

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