Bioterrorism: Field Guide to Disease Identification and by Dag K.J.E. von Lubitz

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By Dag K.J.E. von Lubitz

A superb textual content for both evaluate or for an introductory path for nurses, nursing scholars, physicians, and so forth. Concise, up to date, effortless to take advantage of. sufficiently small to hold within the box in addition. sensible choice for practitioners and professors.

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Additional info for Bioterrorism: Field Guide to Disease Identification and Initial Patient Management

Example text

THE APPEARANCE OF VEE, EEE, AND WEE OUTSIDE THEIR GEOGRAPHICAL RANGES INDICATES THE POSSIBILITY OF A BIOTERRORIST ATTACK. THE INCIDENCE OF SEVERE INFECTIONS WOULD BE SIGNIFICANTLY HIGHER IF AN AEROSOLIZED VIRUS SERVED AS A BIOTERRORIST WEAPON DUE TO DIRECT INFECTION OF THE OLFACTORY NERVE AND SUBSEQUENT RAPID MIGRATION TO THE CENTRAL NERVOUS SYSTEM. E. E. E. fm Page 52 Friday, August 8, 2003 8:14 AM Western Equine Encephalitis (WEE) Infants and elderly are particularly vulnerable (£10% mortality rate).

Fm Page 27 Friday, August 8, 2003 8:14 AM Ⅲ Ⅲ Ⅲ Ⅲ Ⅲ Ⅲ Ⅲ Ⅲ Ⅲ No tears, sunken eyes Absent or barely palpable pulse Hypotension Tachycardia Tachypnea Hypercapnia Hypothermia Hypoglycemia (lethal complication in children) Acidosis (possibility of normal serum [K+] in children when first seen; hypokalemia may develop when acidosis is corrected) Ⅲ Spasmodic muscle contractions when supplying nerves are tapped (Chvostek/Trusseau signs) often present Differential Diagnosis Ⅲ Gastroenteritis – Bacillus cereus – Clostridium perfringens – Escherichia coli – Staphylococcus aureus Ⅲ Other Vibrio infections Laboratory Tests Stool Microscopy Ⅲ Gram stain negative Ⅲ Characteristic motility only in dark field phase contrast microscopy Stool Culture Ⅲ Use TCBS (thiosulphate-citrate-bile-sucrose) medium; large, smooth, round, and yellow colonies Ⅲ Many media used to culture enteric bacteria do not support V.

Combinations have been reported. Melioidiosis may remain dormant following primary infection. Patients may exhibit the acute form several years later. Immunological compromise is often associated. High infection rates caused by aerosols from cultures have been observed in laboratory workers, and cases of person-to-person transmission have been reported. E. E. fm Page 32 Friday, August 8, 2003 8:14 AM Ⅲ Irregular staining in methylene blue Ⅲ Blood cultures usually negative Ⅲ Agglutination tests are difficult interpretation due to high background titers Ⅲ Complement fixation test in melioidiosis: fourfold increase in titer is considered positive; a single titer above 1:160 indicates active infection Ⅲ Complement fixation test in glanders: titer ≥1:20 considered positive Treatment Treatment varies depending on the type and severity of the disease.

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