A Practical Manual of Diabetic Retinopathy Management by Peter Scanlon, Stephen Aldington, Charles Wilkinson, David

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By Peter Scanlon, Stephen Aldington, Charles Wilkinson, David Matthews

This functional medical handbook covers the prognosis, therapy - either clinical and surgical - and long term administration of eye difficulties in individuals with diabetes. aimed toward the MDT eager about the care of sufferers with diabetes, it emphasizes the significance of normal screening and early prognosis and provides evidence-based counsel.

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16 Arteriolar narrowing. Arteriolar abnormalities Fig. 18 Arteriovenous nipping. Other arteriolar changes that occur in diabetic retinopathy are: 1 arteriolar narrowing (Fig. 16) 2 opacification of arteriolar walls (‘sheathing and white threads’) (Fig. 17) 3 arteriovenous nipping – narrowing of the venous diameter where it is crossed by a branch artery. It is often a feature of hypertension (Fig. 18). Fibrous proliferation on or within 1 disc diameter of the disc margin Fibrous proliferation at the disc (FPD) is fibrous tissue opaque enough to be seen at the disc or less than 1 disc diameter (DD) from the disc margin with or without accompanying new vessels (Fig.

Complications as common as with T2DM About 20% of all MODY. Mild hyperglycaemia. Non-progressive form of diabetes. Complications mild or none About 60% of all MODY. Commonest of the MODY gene defects. qxd 12/29/08 14:30 Page 22 22 Chapter 2 1 I 2 II 1 1 2 2 3 3 4 P 5 4 III IV Key: = Female = Male Filled = Diabetic = Deceased Fig. 4 Family tree of an HNF1α family. decarboxylase) antibody level was checked and found to be negative. At this point he was investigated for a genetic aetiology and found to have the P291fsinsC mutation of HNF1α.

Matthews © 2009 by Peter H. Scanlon, Charles P. Wilkinson, Stephen J. Aldington and David R. Matthews ISBN: 978-1-405-17035-2 additional categories of maturity-onset diabetes of the young (MODY) and secondary diabetes. 1). It has even been suggested that the dichotomy is false as there is a grey area between the two types1. As a broad generalization, type 1 diabetes occurs in those who are generally younger (so teenagers are more likely to have type 1, and those in middle age type 2) and thinner (so being overweight is a risk for type 2 diabetes and not for type 1).

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